14 pts refractory AOSD pts (Yamaguchi+) showed a good response to usual doses of tofacitinib. 7/14 complete remission, 6/14 partial remission & 1 relapse w/ pred reduction. May work by reducing reducing IL-6, IL-10, IFN-γ, IFN-α, GM-CSF, neutrophils. https://t.co/rUNoxJdDi5
StillsNow
An educational site for Physicians and Patients with Still's disease (systemic juvenile idiopathic arthritis), periodic fever syndromes and autoinflammatory diseases
