@RheumNow #ACR20 abs0083 Whole exome sequencing & HLA allele prediction in 43 Irish CNO pts show increased association w/HLA-B*27:05 (+in 17.5% pts vs 6% of the Irish population). 18.6% w/personal &18.6%family Hx of PSO. 88% of cases w/multifocal disease, 51% failed 1st line Rx