Early, Aggressive and Seropositive (7.22.2022)
Dr. Jack Cush covers the news and journal reports from the past week on…
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Holes in TH17 cells release IL-1α on NLRP3 activation
Certain T cells can secrete cytokines that are normally part of the innate immune…
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Best of 2023: LAVLI – A New Autoinflammatory Disorder
Editor’s note: this article originally appeared March 28, 2023, and is being shared again…
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I Can't Treat Ugly (9.20.2024)
Dr. Jack Cush reviews the news, journal articles and a new FDA approval for…
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Polyautoimmunity: axSpA and Familial Mediterranean Fever
Mysteries behind polyautoimmunity have confounded rheumatologists for decades. One such association, the co-existence of…
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Still's disease: paediatrics to adults, a continuum or not?
Still’s disease is a rare inflammatory disorder, affecting less than 1 person per 2000…
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Disease Activity Scoring in Adult-onset Still's disease
Still’s disease in adults (AOSD) or children (sJIA) can have dramatic symptom severity, making…
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VEXAS may be more common than expected
A great study of a recently described rheumatologic/hematologic disorder VEXAS (vacuoles, E1-ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic) syndrome recently…
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Best of 2023: EULAR/ACR Guidance on Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome
Editor’s note: this article originally appeared July 26, 2023, and is being shared again…
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EULAR/PReS Still's Disease Management Recommendations
Since 2022, EULAR and the Paediatric Rheumatology European Society (PReS) have been working to…
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